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An significant interaction effect of GSH and position on the ratio of CYS/CYSS was found on d5 ( p interaction = 0.013, Figure 2F) whilst only a significant position effect on d14 ( p position = 0.019, Figure 2F)

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compositions comprise a skin- lightening agent selected from the group of hydroquinone, monobenzyl ether of hydroquinone, azelaic acid, kojic acid, mequinol, retinoids e.g., tretinoin, adapalene), soy proteins, alpha-hydroxy acids e.g., glycolic acid), trichloroacetic acid, salicylic acid, hydroquinone-beta-D-glucopyranoside, paper mulberry, glabridin, 4-isopropylcetchol, aleosin, N-acetyl-4-S-cycteaminylphenol, N-propionyl-4-S- cysteaminylphenol, N-acetyl glucosamine, tranexaminc acid, licorice extract (e.g., Glycyrrhiza Glabra (licorice) root extract), an alpha MSH antagonist (e.g

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